Ok. I've done the water change, tested the pH (7.4), fasted him for 2 days, checked the Ammonia level, it was 0ppm. Fred's condition has not changed. I'm at a loss. Next is to test the Nitrates and Nitrites? I'm organising to off load the juvinile Bristlenoses to Aquariums and giving the Male away to a friend. From more reading I've done, Fred does not match Ammonia poisoning or Nitrite poisoning. Any ideas? The fasting has not helped him any.